5 June 2026, marks a historic milestone in South Africa’s fight against HIV, as Mpumalanga becomes the first province in the country to receive and administer Lenacapavir, a groundbreaking long-acting HIV prevention injection poised to reshape national prevention efforts.
Earlier this morning, Mpumalanga led this national rollout with the first-ever administration of Lenacapavir, given to 21-year-old Jane Mndebele from Embalenhle, who courageously volunteered to become the first person in South Africa to receive this pioneering HIV prevention medication, marking a defining moment in the country’s public health journey.
The fact that Mpumalanga is the first province to both receive and administer Lenacapavir underscores the significance of this rollout, positioning the province at the forefront of a major advancement in HIV prevention and offering renewed hope in reducing new infections nationwide.
This landmark development highlights South Africa’s commitment to innovative healthcare solutions, with Mpumalanga leading the way in introducing next-generation HIV prevention tools aimed at strengthening community health and curbing the spread of HIV/AIDS.




